Black sesame seeds are a rich source of omega 3 and 6 for brain-boosting properties. It is also the only plant that contains omega, which its amount is several times more omega three than fish oil from deep-sea fish. Black sesame is rich in vitamin B, phosphorus, and calcium higher than vegetables. The calcium content is about 410-485 mg. per 100 grams. (People need 1,000 grams of calcium per day). Sesame contains sesamol, a substance that helps prevent cancer and delay body aging. The most active ingredient recently discovered is Rosmarinic Acid, which reduces inflammation and nourishes joints. Sesame seeds are high in saturated fatty acid. This acid has many benefits, such as reducing cholesterol levels, controlling the redundancy of cholesterol, preventing blood vessels from clotting, preventing heart diseases, and other vascular-related diseases. It also relieves various discomfort symptoms such as insomnia, anorexia, fatigue, weakness, numbness, pain along the body, arms, and legs By eating black sesame helps to resist degeneration and increase cartilage formation. Arthritis is caused by cartilage deterioration. Cartilage is an essential part of the body to carry weight and joints. The development of osteoarthritis drugs is, therefore, in the direction of cartilage treatment. Black sesame seeds contain many phenol compounds, particularly in Lignan substance, which is found in sesamin, sesamol, and sesamolin. The researcher discovered that sesame is effective in treating osteoarthritis.